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Proteins in blood may detect cancer ‘by more than seven years’

by Reporter - May 15 69 Views 0 Comment
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New research suggests that certain proteins found in the blood may serve as an early warning sign for cancer, potentially detecting the disease over seven years before it is officially diagnosed.

A recent study has made a groundbreaking discovery by identifying 618 proteins that are associated with 19 different types of cancer. This finding has the potential to revolutionize cancer detection methods, allowing for much earlier diagnosis and treatment. The implications of this research are immense, as it brings us one step closer to effectively combating these devastating diseases.

Blood samples from approximately 44,000 individuals in the UK Biobank, including over 4,900 people who were later diagnosed with cancer, were examined by researchers at the University of Oxford.

A comparison was made between the proteins of individuals who were later diagnosed with cancer and those who were not. Through this analysis, a total of 618 proteins were identified, which were found to be associated with 19 different types of cancer, such as colon, lung, non-Hodgkin lymphoma, and liver.


A recent study, supported by Cancer Research UK and published in Nature Communications, has made significant discoveries in the field of cancer research. The study identified 107 proteins that are linked to cancers diagnosed more than seven years after the collection of the patient's blood sample. Additionally, the researchers found 182 proteins that are strongly associated with a cancer diagnosis within three years.


The authors reached a conclusion that certain proteins have the potential to detect cancer at an earlier stage, opening up new possibilities for treatment. However, additional research is required to validate these findings.


Dr Keren Papier, a senior nutritional epidemiologist at Oxford Population Health at the University of Oxford and joint first author of the study, emphasized the importance of gaining a deeper understanding of the early stages of cancer and the role that blood proteins play in influencing our risk of developing the disease.

 

This knowledge is crucial in our ongoing efforts to save more lives from cancer. Further investigation is necessary to thoroughly examine these proteins and determine their potential for effective prevention.

A recent scientific study examined genetic data from over 300,000 cancer cases and discovered a correlation between 40 specific proteins in the blood and the likelihood of developing nine different types of cancer.

The authors discovered that manipulating these proteins can have varying effects on the likelihood of developing cancer. However, they also noted that this manipulation can sometimes result in unintended side effects.

According to Mark Lawler, a renowned expert in translational cancer genomics and digital health at Queen's University Belfast, the findings of this study are truly remarkable. The ability to detect cancer at an early stage, even before it shows any clinical symptoms, presents a crucial opportunity to intervene and treat the disease with a higher likelihood of success. Moreover, it brings us one step closer to the ultimate goal of preventing cancer from developing in the first place.

There is still more work to be done, but this is a significant advancement in understanding a disease that impacts a large portion of the UK population.

According to Lawrence Young, a professor of molecular oncology at the University of Warwick, the recent findings represent a significant advancement in the search for markers that indicate a higher risk of cancer. Additionally, these findings have the potential to contribute to the early detection of cancer.

Understanding the protein alterations that occur before the onset of cancer is crucial for identifying individuals at risk and gaining valuable knowledge about the underlying causes of cancer.

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